瘦素(LEP)多克隆抗體
Polyclonal Antibody to Leptin (LEP)
OB; OBS; Obesity Homolog; Obesity Factor; Obese Protein
- 編號UPAA084Ga01
- 物種Chicken (Gallus，雞) 相同的名稱，不同的物種。
- 來源多抗制備
- 宿主兔
- 效價-
- Ig類型 IgG
- 純化方式抗原特異性親和純化
- 標記物無標記物
- 免疫原 -
- 緩沖液成份磷酸鹽緩沖液（pH7.4,含有0.02% NaN3和50%甘油）
- 性狀液體
- 濃度500μg/mL
- 且適物種-
- 應用WB; IHC; ICC; IP.
如果抗體需用于流式細胞術，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 308 ¥ 718 ¥ 1026 ¥ 2565 ¥ 10260
- 欲了解實際交易價格和更多情況，請與當地經銷商聯(lián)系!
-
產品包裝(模擬)
-
產品包裝(模擬)
-
通過ISO 9001、ISO 13485質量體系認證
特異性
該抗體是針對LEP的兔多克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別LEP。
用法
免疫印跡：0.2-2μg/mL;1:250-2500
免疫組織化學：5-20μg/mL;1:25-100
免疫細胞化學：5-20μg/mL;1:25-100
最佳稀釋倍數最終由用戶決定。
儲存
經常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產生。保質期內，在適當的條件下存儲，損失率低于5%。
贈品
增值服務
相關產品
| 編號 | 適用物種：Chicken (Gallus，雞) | 應用(僅供研究使用，不用于臨床診斷！) |
| URPA084Ga01 | 瘦素(LEP)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAA084Ga01 | 瘦素(LEP)多克隆抗體 | WB; IHC; ICC; IP. |
| UMAA084Ga21 | 瘦素(LEP)單克隆抗體 | WB; IHC; ICC; IP. |
| USEA084Ga | 瘦素(LEP)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMA084Ga | 瘦素(LEP)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| European Journal of Pharmacology | Puerarin improves insulin resistance and modulates adipokine expression in rats fed a high-fat diet [PubMed: 20869961] |
| Indian Journal of Pharmacology | Effect of Argyreia speciosa root extract on cafeteria diet-induced obesity in rats [Ijp: source] |
| Journal of endocrinology | Testosterone protects from metabolic syndrome-associated prostate inflammation: an experimental study in rabbit [PubMed: 22010203] |
| PLoS One. | Multi-Functional Roles of Chitosan as a Potential Protective Agent against Obesity [PubMed: 23342013] |
| Molecular and Cellular Endocrinology | Soy isoflavones modulate adipokines and myokines to regulate lipid metabolism in adipose tissue, skeletal muscle and liver of male Huanjiang mini-pigs [ScienceDirect: S0303720712004194] |
| Journal of Animal and Feed Sciences | Ovarian, metabolic and endocrine indexes in dairy cows with different body condition scores [Ifzz: Source] |
| British Journal of Nutrition | n-6: n-3 PUFA ratio is involved in regulating lipid metabolism and inflammation in pigs [Pubmed: 23947577] |
| Int J Mol Sci. | Maternal high folic acid supplement promotes glucose intolerance and insulin resistance in male mouse offspring fed a high-fat diet. [Pubmed: 24736781] |
| Endocr J. | CTRP3 modulates the expression and secretion of adipokines in 3T3-L1 adipocytes [Pubmed:25168658] |
| Animal Physiology | EFFECT OF LEPTIN GENE ON SERUM LEPTIN CONCENTRATION AND BEEF QUALITY IN CZECH FLECKVIEH BULLS [Mendelu:Source] |
| Evid Based Complement Alternat Med. | Tinospora crispa Ameliorates Insulin Resistance Induced by High Fat Diet in Wistar Rats [Pubmed:Pmc4363645] |
| general endocrinology | Oxytocin reverse ovariectomy-induced Osteoper and body fat gain [Pubmed:24506069] |
| Respiratory Physiology & Neurobiology | Maternal high-fat diet feeding during pregnancy and lactation augments lung inflammation and remodeling in the offspring [Pubmed:25500158] |
| Sci Rep | Hepatic steatosis depresses alpha-1-antitrypsin levels in human and rat acute pancreatitis [PubMed: 26634430] |
| Evid Based Complement Alternat Med | Tinospora crispa [PubMed: 25821506] |
| Ankara | Effects of breeder age and early energy restriction on fattening performance, some meat quality traits and plasma leptin concentration of broilers [Dergiler: 11] |
| MEDICINA VETERIN | Comparative measurements of the morphometric pattern and energy profile of Crioula mares in the final third of gestation, with different body condition scores [Scielo: S0102-09352015000300707] |
| Pancreatic Disorders & Therapy | Pancreatic Exocrine Insufficiency Affects Not Only Digestibility of Nutrients and Growth, but Also Body Composition and Endocrinological Parameters – Study on Piglets Used As a Model for Children [Journals: 2165-7092-%20S5-00] |
| Veterinary Word | Effect of extended photoperiod during winter on growth and onset of puberty in Murrah buffalo heifers [Pubmed:27051212] |
| Animal | Anterior pituitary influence on adipokine expression and secretion by porcine adipocytes. [Pubmed:27074715] |
| ANNALS OF ANIMAL SCIENCE | Comparison of the effect of a standard inclusion level of inorganic zinc to organic form at lowered level on bone development in growing male Ross broiler chickens [journalprintahead:87] |
| Annals of Animal Science | Comparison of the Effect of a Standard Inclusion Level of Inorganic Zinc to Organic Form at Lowered Level on Bone Development in Growing Male Ross Broiler Chickens [view:87] |
| Obes Surg. | Changes on Adipose Tissue Distribution After Laparoscopic Roux-en-Y Gastric Bypass in Obese G?ttingen Minipig. Effects on Glucose Metabolism. [Pubmed:27185175] |
| Acta Histochemica | Favorable outcomes of hydroxychloroquine in insulin resistance may be accomplished by adjustment of the endothelial dysfunction as well as the skewed balance of adipokines [science:S0065128116301234] |
| J Biomed Mater Res A | Nanosized titanium dioxide resulted in the activation of TGF-β/Smads/p38MAPK pathway in renal inflammation and fibration of mice [Pubmed:26850371] |
| Clin Epigenetics. | The bromodomain inhibitor N-methyl pyrrolidone reduced fat accumulation in an ovariectomized rat model [Pubmed:27110299] |
| International Journal of Molecular Sciences | Oral Supplementation with a Special Additive of Retinyl Palmitate and Alpha Tocopherol Reduces Growth Retardation in Young Pancreatic Duct Ligated Pigs Used as a Model for Children Suffering from Exocrine Pancreatic Insufficiency [pubmed:27690005] |
| Journal of Animal Science | Changes in small intestinal morphometry and electrogenic nutrient transport in young pigs with pancreatic exocrine insufficiency [publications:jas] |
| International Journal of Endocrinology | The Changes of Serum Leptin and Kisspeptin Levels in Chinese Children and Adolescents in Different Pubertal Stages [pubmed:27990162] |
| journal of animal science | The effect of GnRH vaccination on performance, carcass, and meat quality and hormonal regulation in boars, barrows, and gilts. [pubmed:27482668] |
| journal of animal science | Diet-induced modifications to milk composition have long-term effects on offspring growth in rabbits. [pubmed:28380600] |
| Evidence-Based?Complementary and Alternative?Medicine | Four-Week?Consumption?of?Malaysian?Honey?Reduces?Excess?Weight?Gainand?Improves?Obesity-Related?Parameters?in High Fat Diet?Induced?ObeseRats. [pubmed:28246535] |
| Asian-Australasian Journal of?Animal Sciences | Dietary Niacin Supplementation Suppressed Hepatic Lipid Accumulation in Rabbits [pubmed:27004817] |
| Stem?Cell?Research?&?Therapy | Serial?changes?in the?proliferation?and?differentiation?of?adipose-derived?stem?cells?after?ionizingradiation. [pubmed:27530249] |
| Obesity Surgery | Changes?on?Adipose Tissue?Distribution?After?Laparoscopic?Roux-en-Y Gastric Bypass?in?ObeseG?ttingen?Minipig.?Effects?on?Glucose?Metabolism. [pubmed:27185175] |
| Meat Sci | Estimation of the intramuscular fat content of m. longissimus thoracis in crossbred beef cattle based on live animal measurements. [pubmed:27940421] |
| THE INDIAN JOURNAL OF VETERINARY SCIENCES AND BIOTECHNOLOGY | Correlation of Leptin, Insulin and Glucose During Late Gestation and Early Lactation in Murrah Buffaloes [7086] |
| Journal of Animal and Plant Sciences | Effects Of Maca (Lep?d?um Meyen?? Walp) Powder On Serum Ind?ces And Metabol?c Responses In Racehorses [57cf073008ae83b37462323a.pdf] |
| Biological Trace Element Research | Effect of Dietary Phytase Supplementation on Bone and Hyaline Cartilage Development of Broilers Fed with Organically Complexed Copper in a Cu-Deficient Diet [article:10.1007] |
| Revista Brasileira de Ciência Avícola | Effect of Zinc Level and Source (Zinc Oxide Vs. Zinc Glycine) on Bone Mechanical and Geometric Parameters, and Histomorphology in Male Ross 308 Broiler Chicken [10.159:1806-9061-2016-0285] |
| Applied Animal Behaviour Science | Evaluating measures of exploratory behaviour in sows around farrowing and during lactation? A pilot study [10.1016/j.jacl.2017.03.007] |
| Proceedings of the National Academy of?Sciences?of the United States of America (PNAS) | cAMP-inducible coactivator CRTC3 attenuates brown adipose tissue thermogenesis [Pubmed:29784793] |
| Oxidative?Medicine?and?Cellular?Longevity | Changes of Plasma FABP4, CRP, Leptin, and Chemerin Levels in relation to Different Dietary Patterns and Duodenal-Jejunal Omega Switch Surgery in Sprague?… [Pubmed:29849871] |
| Frontiers in Endocrinology | Circulating and Adipose Tissue mRNA Levels of Zinc-α2-Glycoprotein, Leptin, High-Molecular-Weight Adiponectin, and Tumor Necrosis Factor-Alpha in?… [Pubmed:29755407] |
| Journal of Agricultural and?Food?Chemistry | Metabolomics for the effect of biotin and nicotinamide on transition dairy cows [Pubmed:29758980] |
| Frontiers in Physiology | Ileal Transposition Surgery Decreases Fat Mass and Improves Glucose Metabolism in Diabetic GK Rats: Possible Involvement of FGF21 [Pubmed:29593555] |
| Bioscience Reports | Effect of maternal hypothyroidism during pregnancy on insulin resistance, lipid accumulation and mitochondrial dysfunction in skeletal muscle of fetal rats [Pubmed:29784871] |
| Neurochemical?Research | The leptin, dopamine and serotonin receptors in hypothalamic POMC-neurons of normal and obese rodents [Pubmed:29397535] |
| PLoS One | Subsequent somatic axis and bone tissue metabolism responses to a low-zinc diet with or without phytase inclusion in broiler chickens [Pubmed:29373588] |
| Biochemical and Biophysical Research Communications | Chronic cold exposure results in subcutaneous adipose tissue browning and altered global metabolism in Qinghai-Tibetan plateau pika (Ochotona curzoniae) [Pubmed:29626477] |
| Alcohol?and?Alcoholism | Leptin Expression and Gene Methylation Patterns in Alcohol-Dependent Patients with Ethyltoxic Cirrhosis—Normalization After Liver Transplantation and Implications?… [Pubmed:29912265] |
| Iranian?Red?Crescent?Medical?Journal? | The Effect of Aerobic Training on Tumor Growth, Adiponectin, Leptin and Ghrelin in Mice with Breast Cancer [ircmj-20-03-13305.pdf] |
| Pakistan Journal of Zoology | Effects of Intrauterine Growth Retardation on Growth, Meat Quality and Muscle Fiber Composition of Pigs. [:] |
| Oncotarget | Epigallocatechin-3-gallate suppresses differentiation of adipocytes via regulating the phosphorylation of FOXO1 mediated by PI3K-AKT signaling in 3T3-L1?… [Pubmed:29484120] |
| УСПЕХИ ГЕРОНТОЛОГИИ | ВЛИЯНИЕ МЕТФОРМИНА НА МЕТАБОЛИЧЕСКИЕ ПОКАЗАТЕЛИ И ГИПОТАЛАМИЧЕСКИЕ СИГНАЛЬНЫЕ СИСТЕМЫ У КРЫС С ОЖИРЕНИЕМ?… [AG_2018-31-01.pdf] |
| Food Science and Technology Research | Combinational Effect of Pine Needle Polysaccharide and Kudzu Flavonoids on Cell Differentiation and Fat Metabolism in 3T3-L1 Cells [Doi: 10.3136/fstr.24.903] |
| Nutrients | Effects of Metformin Combined with Lactoferrin on Lipid Accumulation and Metabolism in Mice Fed with High-Fat Diet [Pubmed: 30400147] |
| Psychopharmacology | Betahistine effects on weight-related measures in patients treated with antipsychotic medications: a double-blind placebo-controlled study [Pubmed: 30382354] |
| Progress in Nutrition | Effect of fermented food consumption on biochemical parameters and adipokines levels [Doi: 0.23751/pn.v20i4.7374] |
| THE INDIAN JOURNAL OF VETERINARY SCIENCES & BIOTECHNOLOGY | THE INDIAN JOURNAL OF VETERINARY SCIENCES & BIOTECHNOLOGY [] |
| Biomedicine & Pharmacotherapy | Raspberry ketone and Garcinia Cambogia rebalanced disrupted insulin resistance and leptin signaling in rats fed high fat fructose diet [Pubmed: 30530230] |
| Nutrition in the Prevention and Treatment of Abdominal Obesity | Effects of Diet-Induced Early-Stage Obesity on a Low-Testosterone Gottingen Minipig [] |
| Scientific Reports | Obesity Aggravates Acute Pancreatitis via Damaging Intestinal Mucosal Barrier and Changing Microbiota Composition in Rats [Pubmed: 30635594] |
| Atherosclerotic diseases | Cardiotrophin-1 and leptin as cardiovascular risk markers in male patients with obstructive sleep apnea syndrome [Pubmed: 30775602] |
| PLoS One | Impact of exposure to diesel exhaust during pregnancy on mammary gland development and milk composition in the rabbit [Pubmed: 30763367] |
| Scientific Journal of Kurdistan University of Medical Sciences | Effect of High Intensity Interval Training (HIIT) on visceral and subcutaneous levels of leptin and plasma insulin and glucose in male Wistar rats [] |
| PLOS?ONE | The evidence of metabolic-improving effect of metformin in Ay/a mice with genetically-induced melanocortin obesity and the contribution of hypothalamic?… [Pubmed: 30870482] |
| International Journal of Pharmaceutical Research & Allied Sciences | Osteoprotegerin Levels among Saudi Cardiovascular Patients. [] |
| Journal of Ethnopharmacology | Anti-obesity effect of argel (Solenostemma argel) on obese rats fed a high fat diet [] |
| Gene | Expression of adipokines and their receptors in adipose tissue of women with class 3 obesity with or without hypertension [Pubmed: 30940525] |
| 中國藥理學通報 | 冷暴露對高脂飲食小鼠脂肪棕色化的影響 [] |
| Arch Physiol Biochem | Associations of apelin, leptin, irisin, ghrelin, insulin, glucose levels, and lipid parameters with physical activity during eight weeks of regular exercise training [Pubmed: 31290696] |
| Food & Function | A dietary polysaccharide from Eucheuma cottonii downregulates proinflammatory cytokines and ameliorates osteoarthritis-associated cartilage degradation in obese?… [] |
| Nutrients | High-dose Glycerol Monolaurate Up-Regulated Beneficial Indigenous Microbiota without Inducing Metabolic Dysfunction and Systemic Inflammation: New Insights?… [] |
| Developmental Dynamics | Puberty is a critical window for the impact of diet on mammary gland development in the rabbit [Pubmed: 31348557] |
| Adv Gerontol | The Effect of Different Types of Bariatric Surgery on Metabolic and Hormonal Parameters in Rats with a Decompensated Form of Type II Diabetes Mellitus [Pubmed: 31228372] |
| Proceedings of the Royal Society B: Biological Sciences | Paternal chronic folate supplementation induced the transgenerational inheritance of acquired developmental and metabolic changes in chickens [Pubmed: 31506054] |
| Food & Function | Collaborative Effects of Chlorogenic Acid and Caffeine on Lipid Metabolism via AMPKα-LXRα/SREBP-1c Pathway in High-Fat Diet-Induced Obese Mice [Pubmed: 31670366] |
| journal of ethnopharmacology | Dietary supplementation of Morus nigra L. leaves decrease fat mass partially through elevating leptin-stimulated lipolysis in pig model [Pubmed: 31756448] |
| Annals of Nutrition and Metabolism | Serum Asprosin Concentrations Are Increased and Associated with Insulin Resistance in Children with Obesity [Pubmed: 31775140] |
| Journal of Ethnopharmacology | Upregulation of MC4R and PPAR-α expression mediates the anti-obesity activity of Moringa oleifera Lam. in high-fat diet-induced obesity in rats [Pubmed: 31911179] |
| Journal of Natural Products | Prenylated Phenolic Compounds from the Aerial Parts of Glycyrrhiza uralensis as PTP1B and α-Glucosidase Inhibitors [Pubmed: 32196343] |
| gynecological endocrinology | Salivary Leptin and Chemerin; a novel way of gestational diabetes screening [Pubmed: 32274942] |
| Frontiers in Endocrinology | RFRP-3, the Mammalian Ortholog of GnIH, Is a Novel Modulator Involved in Food Intake and Glucose Homeostasis [Pubmed: 32328034] |
| Ann Nutr Metab | Copeptin and Nesfatin-1 Are Interrelated Biomarkers with Roles in the Pathogenesis of Insulin Resistance in Chinese Children with Obesity [Pubmed: 33027789] |
| ANDROLOGIA | The effect of metformin treatment on the basal and gonadotropin‐stimulated steroidogenesis in male rats with type 2 diabetes mellitus [Pubmed: 32951228] |
| GENERAL AND COMPARATIVE ENDOCRINOLOGY | Adipokines expression profiles in both plasma and peri renal adipose tissue in Large White and Meishan sows: a possible involvement in the fattening and?… [Pubmed: 32827511] |
| Nutrition & Diabetes | C-Peptide and leptin system in dichorionic, small and appropriate for gestational age twins—possible link to metabolic programming? [Pubmed: 32778645] |
| BIOLOGICAL TRACE ELEMENT RESEARCH | Ameliorative Effect of Ananas comosus on Cobalt Chloride-Induced Hypoxia in Caco2 cells via HIF-1α, GLUT 1, VEGF, ANG and FGF [Pubmed: 32654099] |
| plos one | Serum leptin level is associated with phase angle in CKD5 patients not undergoing dialysis [Pubmed: 30089154] |
| Journal of reproduction and fertility | Blastomere removal affects homeostatic control leading to obesity in male mice [Pubmed: 33112292] |
| Journal of Evolutionary Biochemistry and Physiology | The Effect of Diet-Induced and Melanocortin Obesity on Expression of Tryptophan Hydroxylase 2 in the Dorsal Raphe Nucleus and Ventral Tegmental Area in Mice [] |
| Indian Journal of Animal Sciences | Peripheral concentrations of metabolic and inflammatory indicators during transition period and their relationship with postpartum clinical endometritis in dairy?… [] |
| СОСТОЯНИЕ МЕЛАТОНИН-АССОЦИИРОВАННОЙ ГОРМОНАЛЬНОЙ СИСТЕМЫ У ДЕТЕЙ С ИЗБЫТОЧНОЙ МАССОЙ ТЕЛА [] | |
| biorxiv | Altered hematopoietic system and self-tolerance in Bardet-Biedl Syndrome [] |
| The Egyptian Journal of Neurology, Psychiatry and Neurosurgery?volume | Serum leptin and body mass index in a sample of Egyptian multiple sclerosis patients [] |
| Biosci Rep | A 12-week aerobic exercise improves metabolic function with lower adipose tissue and ectopic fat in high fat diet fed rats [33432988] |
| Cell Metab | TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease [34107313] |
| International Journal of Endocrinology | Effect of Ileal Transposition (IT) on Angiopoietin-Like Protein-8 (ANGPTL8) and Pentraxin (PTX3) Plasma Level in Sprague-Dawley Rats Fed High-Fat Diet??- [34035808] |
| EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY | Different Ratios of Corn and Coconut Oil Blends in High?\Fat Diets Influence Fat Deposition without Altering Metabolic Biomarkers in Male Rats [] |
| The pharma innovation Journal | Comparative study on genital status, energy balance and mineral content of swamp buffalo (Luit) heifers and cows under organized system of rearing in Assam??- [] |
| Indian Journal of Forensic Medicine & Toxicology | Altered Serum Marker of Adipokines Profile in Breast Cancer Women [] |
| PPAR Research | Activation of the Peroxisome Proliferator-Activated Receptors (PPAR-α/γ) and the Fatty Acid Metabolizing Enzyme Protein CPT1A by Camel Milk Treatment?… [34306045] |
| Br J Nutr | The Association of Pre-Pregnancy BMI On Leptin, Ghrelin, Adiponectin, and IGF-1 In Breast Milk, A Case Control Study [34348809] |
| Ann Med Surg (Lond) | Maternal and fetal serum leptin levels and their association with maternal and fetal variables and labor: A cross-sectional study [34815864] |
| Biofactors | Vitamin D3 enhances the effects of omega‐3 oils against metabolic dysfunction‐associated fatty liver disease in rat [34767670] |
| Nat Commun | GP73 is a TBC-domain Rab GTPase-activating protein contributing to the pathogenesis of non-alcoholic fatty liver disease without obesity [34853313] |
| Int J Mol Sci | The Effects of Separate and Combined Treatment of Male Rats with Type 2 Diabetes with Metformin and Orthosteric and Allosteric Agonists of Luteinizing Hormone?… [Pubmed:35008624] |
| Bull Exp Biol Med | Comparative Study of the Restoring Effect of Metformin, Gonadotropin, and Allosteric Agonist of Luteinizing Hormone Receptor on Spermatogenesis in Male Rats with?… [Pubmed:35175480] |
| Naunyn Schmiedebergs Arch Pharmacol | Intragastric safflower yellow and its main component HSYA improve leptin sensitivity before body weight change in diet-induced obese mice [Pubmed:35201390] |
| npj Biofilms and Microbiomes | The microbiota-gut-kidney axis mediates host osmoregulation in a small desert mammal [Pubmed:35379849] |
| Ecotoxicol Environ Saf | Monochromatic blue light not green light exposure is associated with continuous light-induced hepatic steatosis in high fat diet fed-mice via oxidative stress [Pubmed:35588616] |
| Biomed Res Int | Seahorse Protein Hydrolysate Ameliorates Proinflammatory Mediators and Cartilage Degradation on Posttraumatic Osteoarthritis with an Obesity Rat Model [Pubmed:35509713] |
| Endocr J | A novel anti-obesity mechanism for liraglutide by improving adipose tissue leptin resistance in high-fat diet-fed obese mice [Pubmed:35705299] |
| Impact of pre-breeding feeding practices on rabbit mammary gland development at mid-pregnancy. [] | |
| High Circulating Fibroblast Growth Factor-21 Levels as a Prognostic Marker in Fatty Pancreas Patients [] | |
| Dairy Cattle Physiology Division ICAR-National Dairy Research Institute, Karnal-132001, Haryana, India Corresponding Authors Email ID: menalsh08vets?… [] | |
| Scientific Reports | SARS-CoV2 Induced Biochemical Mechanisms in Liver Damage and Intestinal Lesions. [] |
留言咨詢
