脂質(zhì)運(yùn)載蛋白2(NGAL)真核蛋白
Eukaryotic Neutrophil gelatinase-associated lipocalin (NGAL)
Lipocalin-2; LCN2; p25; Lipocalin 2; Oncogene 24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; Siderocalin LCN2
- 編號UEPB388Mu61
- 物種Mus musculus (Mouse，小鼠) 相同的名稱，不同的物種。
- 來源真核表達(dá)
- 宿主293F cell
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細(xì)胞定位分泌
- 預(yù)測分子量22.5kDa
- 實際分子量27kDa(差異分析請參閱說明書)
- 片段與標(biāo)簽Gln21~Asn200 with N-terminal His Tag
- 緩沖液成份PBS, pH7.4, containing 5% Trehalose.
- 性狀凍干粉
- 純度> 90%
- 等電點9.2
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure . Gene Sequencing (extract)
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Figure. SDS-PAGE
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通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Mus musculus (Mouse，小鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| UAPB388Mu01 | 脂質(zhì)運(yùn)載蛋白2(NGAL)活性蛋白 | Cell?culture;?Activity?Assays. |
| UAPB388Mu61 | 脂質(zhì)運(yùn)載蛋白2(NGAL)活性蛋白 | Cell?culture;?Activity?Assays. |
| URPB388Mu02 | 脂質(zhì)運(yùn)載蛋白2(NGAL)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UEPB388Mu61 | 脂質(zhì)運(yùn)載蛋白2(NGAL)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPB388Mu01 | 脂質(zhì)運(yùn)載蛋白2(NGAL)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAB388Mu01 | 脂質(zhì)運(yùn)載蛋白2(NGAL)多克隆抗體 | WB; IHC |
| UPAB388Mu02 | 脂質(zhì)運(yùn)載蛋白2(NGAL)多克隆抗體 | WB; IHC; ICC; IP. |
| ULAB388Mu81 | 脂質(zhì)運(yùn)載蛋白2(NGAL)多克隆抗體(異硫氰酸熒光素標(biāo)記) | WB; IHC; ICC; IF. |
| ULAB388Mu71 | 脂質(zhì)運(yùn)載蛋白2(NGAL)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| USEB388Mu | 脂質(zhì)運(yùn)載蛋白2(NGAL)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| USCB388Mu | 脂質(zhì)運(yùn)載蛋白2(NGAL)檢測試劑盒(化學(xué)發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| ULMB388Mu | 脂質(zhì)運(yùn)載蛋白2(NGAL)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
| UKSB388Mu01 | 脂質(zhì)運(yùn)載蛋白2(NGAL)檢測試劑盒DIY材料(酶聯(lián)免疫吸附試驗法) | Main materials for "Do It (ELISA Kit) Yourself". |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
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| International Journal of Endocrinology | Cholesterol Contributes to Diabetic Nephropathy through SCAP-SREBP-2 Pathway [Pubmed: 24369464] |
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| Asian Journal of Sports Medicine | Effects of Resistance versus Endurance Training on Plasma Lipocalin-2 in Young Men [Tums: Source] |
| European Respiratory Journal | Differences in plasma and sputum biomarkers between COPD and COPD-asthma overlap [Pubmed: 23794464] |
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| PLoS One | Ameliorative Effect of Chrysin on Adenine-Induced Chronic Kidney Disease in Rats [PubMed: 25909514] |
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| Int Wound J. | From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases. [Pubmed:26991748] |
| Archives of Biological Sciences | Diabetes-induced renal failure is associated with tissue inflammation and neutrophil gelatinase-associated lipocalin: Effects of resveratrol [publication:299492265_Diabetes-induced_renal_failu] |
| International Journal of Molecular Medicine | The neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats [pubmed:27430552] |
| Hepatology. | Hyperoxidized albumin modulates neutrophils to induce oxidative stress and inflammation in severe alcoholic hepatitis. [pubmed:27775820] |
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| Scientific Reports | Hemojuvelin Predicts Acute Kidney Injury and Poor Outcomes Following Cardiac Surgery [Pubmed:29386545] |
| Life?Sciences | Pyrrolidine dithiocarbamate inhibits mouse acute kidney injury induced by diclofenac by targeting oxidative damage, cytokines and NF-κB activity [Pubmed:30036488] |
| Molecules | Effect of Pinocembrin Isolated from Mexican Brown Propolis on Diabetic Nephropathy [Pubmed:29642511] |
| American Journal of Translational?Research | Improved approach for normothermic machine perfusion of cold stored kidney grafts [Pubmed:30018731] |
| Chronic obstructive pulmonary disease (COPD)--from biomarkers to clinical phenotypes [ISBN:978-951-51-4039-5] | |
| Disease Markers | Potential Novel Biomarkers of Obstructive Nephropathy in Children with Hydronephrosis [Doi: 10.1155/2018/1015726] |
| Kidney?and?Blood?Pressure?Research | The Kidney Specific Protein myo-Inositol Oxygenase, a Potential Biomarker for Diabetic Nephropathy [Pubmed: 30504713] |
| BMC?Complementary and Alternative Medicine | Dual actions on gout flare and acute kidney injury along with enhanced renal transporter activities by Yokuininto, a Kampo medicine [Pubmed: 30871515] |
| Naunyn-Schmiedeberg's archives of pharmacology | Piceatannol protects against cisplatin nephrotoxicity via activation of Nrf2/HO-1 pathway and hindering NF-κB inflammatory cascade [Pubmed: 31197431] |
| Diabetes, Metabolic Syndrome and Obesity | A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation [Pubmed: 31447572] |
| Environment International | Toxicity assessment due to prenatal and lactational exposure to lead, cadmium and mercury mixtures [Pubmed: 31639605] |
| Scientific Reports | Alkaline phosphatase treatment of Acute Kidney injury in an infant piglet Model of cardiopulmonary Bypass with Deep Hypothermic circulatory Arrest [Pubmed: 31578351] |
| Int Urol Nephrol | The evaluation of acute kidney injury due to ischemia by urinary neutrophil gelatinase-induced lipocalin (uNGAL) measurement in patients who underwent partial?… [Pubmed: 32980930] |
| human & experimental toxicology | Upregulated miR-101 inhibits acute kidney injury–chronic kidney disease transition by regulating epithelial–mesenchymal transition [Pubmed: 32633566] |
| INTERNATIONAL JOURNAL OF ENDOCRINOLOGY | CОСТОЯНИЕ ТИРЕОИДНОЙ ФУНКЦИИ У ПАЦИЕНТОВ С САХАРНЫМ ДИАБЕТОМ 1-ГО ТИПА И ХРОНИЧЕСКОЙ БОЛЕЗНЬЮ ПОЧЕК?… [] |
| INTERNATIONAL JOURNAL OF ENDOCRINOLOGY | Thyroid function in patients with type 1 diabetes mellitus and chronic kidney disease receiving renal replacement therapy [] |
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| ARCHIVES OF TOXICOLOGY | Nrf2 deficiency aggravates the kidney injury induced by subacute cadmium exposure in mice [33398418] |
| Biomed Res Int | Renal Protective Effect of Beluga Lentil Pretreatment for Ischemia-Reperfusion Injury [33604384] |
| International Journal of Medical Sciences | Elevated plasma level of neutrophil gelatinase-associated lipocalin (NGAL) in patients with breast cancer [34104101] |
| Intensive Care Medicine Experimental | Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental?… [34169407] |
| Biomolecules | Preservation of Mitochondrial Coupling and Renal Function by Controlled Oxygenated Rewarming of Porcine Kidney Grafts [34944524] |
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