血管內(nèi)皮生長因子A(VEGFA)真核蛋白
Eukaryotic Vascular Endothelial Growth Factor A (VEGFA)
VEGF; VEGF-A; VPF; Vascular Endothelial Cell Growth Factor A; Vascular Permeability Factor
- 編號(hào)UEPA143Bo61
- 物種Bos taurus; Bovine (Cattle，牛) 相同的名稱，不同的物種。
- 來源真核表達(dá)
- 宿主293F cell
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細(xì)胞定位分泌
- 預(yù)測分子量45.1kDa
- 實(shí)際分子量46kDa(差異分析請(qǐng)參閱說明書)
- 片段與標(biāo)簽Ala27~Arg146 with N-terminal His Tag and C-terminal Fc Region of Human IgG1
- 緩沖液成份PBS, pH7.4, containing 5% Trehalose.
- 性狀凍干粉
- 純度> 95%
- 等電點(diǎn)6.9
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價(jià)格 ¥ 756 ¥ 1890 ¥ 3780 ¥ 11340 ¥ 28350
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure. SDS-PAGE
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通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過一個(gè)月，-80°C不超過12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
贈(zèng)品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Bos taurus; Bovine (Cattle，牛) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| UEPA143Bo61 | 血管內(nèi)皮生長因子A(VEGFA)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPA143Bo01 | 血管內(nèi)皮生長因子A(VEGFA)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAA143Bo01 | 血管內(nèi)皮生長因子A(VEGFA)多克隆抗體 | WB; IHC; ICC; IP. |
| USEA143Bo | 血管內(nèi)皮生長因子A(VEGFA)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMA143Bo | 血管內(nèi)皮生長因子A(VEGFA)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
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| Acta Biomaterialia | Preparation and characterization of pro-angiogenic gel derived from small intestinal submucosa [article:S1742706115301410] |
| Acta Biomaterialia | Antioxidant and bone repair properties of quercetin-functionalized hydroxyapatite: An in vitro osteoblast–osteoclast–endothelial cell co-culture study [Pubmed:26689470] |
| Alcohol | The effects of ethanol on angiogenesis after myocardial infarction, and preservation of angiogenesis with rosuvastatin after heavy drinking [Pubmed:27565753] |
| American Journal of Biomedical Sciences | Insulin Like Growth Factor -1(IGF-1) Promotes Angiogenesis and Reverses Ischemia Reperfusion Induced Acute Kidney Injury in Rats: Role of VEGF and TGF-β1 [publication:303524932_Insulin_Like_Growth_Factor_-] |
| 臨床合理用藥 2016 年 8 月第 9 卷第 8A 期 | 袖帶法缺血訓(xùn)練對(duì)單支冠狀動(dòng)脈慢性完全閉塞病變患者心肌缺血及左心室功能的影響 [58477c05699e4.pdf] |
| The Royal Society of Chemistry | Effects of immobilized VEGF on endothelial progenitor cells cultured on silicon substituted and nanocrystalline hydroxyapatites [c6ra19154a] |
| J Cell Physiol. | An advanced tri-culture model to evaluate the dynamic interplay among osteoblasts, osteoclasts, and endothelial cells. [pubmed:28240358] |
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| Tumor Biology | Antiangiogenic activity of vitexicarpine in experimentally induced hepatocellular carcinoma: Impact on vascular endothelial growth factor pathway [pubmed:28651490] |
| 臨床輸血與檢驗(yàn) | 聯(lián)合檢測血清血管內(nèi)皮生長因子和β-HCG對(duì)早期異位妊娠的診斷意義 [1671-2587] |
| Journal of Histochemistry & Cytochemistry | Hyperglycemia Alters the Protein Levels of Prominin-1 and VEGFA in the Retina of Albino Rats [pubmed:29076766] |
| Chinese Medicial Journal | Safflower Extract and Aceglutamide Injection Promoting Recovery of Peripheral Innervations via Vascular Endothelial Growth Factor-B Signaling in Diabetic Mice [PMC5717862] |
| Stem Cell Research & Therapy | Effects of low-intensity pulsed ultrasound (LIPUS)-pretreated human amnion-derived mesenchymal stem cell (hAD-MSC) transplantation on primary ovarian insufficiency in rats [10.1186/s13287-017-0739-3] |
| Scientific Reports | Advanced glycation end products promote VEGF expression and thus choroidal neovascularization via Cyr61-PI3K/AKT signaling pathway [pubmed:29097668] |
| Translational Cancer Research | Preliminary study of the treatment effect of apatinib mesylate upon malignant ascites and its safety [10.21037/tcr.2017.08.24] |
| Journal of Controlled Release | A DPP-IV-resistant glucagon-like peptide-2 dimer with enhanced activity against radiation-induced intestinal injury [pubmed:28522195] |
| ANTICANCER RESEARCH | Functional Characterization of VEGF- and FGF-induced Tumor Blood Vessel Models in Human Cancer Xenografts [pubmed:29187438] |
| Journal of Biomaterials and Tissue Engineering | The Combination of Acellular Porcine Small Intestinal Submucosa (SIS) Cryogel Granules and Adipose Tissue Improves the Survival Ratio of Fat Grafting in Mice [10.1166/jbt.2017.1652] |
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| Stem Cell Research and Therapy | c-kit Positive Cardiac Outgrowth Cells Demonstrate Better Ability for Cardiac Recovery Against Ischemic Myopathy. [pubmed:29238626] |
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| Bulletin?of Experimental?Biology?and?Medicine | Expression of Hif-1α, Nf-κb, and Vegf Genes in the Liver and Blood Serum Levels of HIF-1α, Erythropoietin, VEGF, TGF-β, 8-Isoprostane, and Corticosterone in Wistar Rats with High and Low Resistance to Hypoxia. Corticosterone in?… [Pubmed: 30353332] |
| Clinical Significance of Nectin-4 Expression in Metastasis and Angiogenesis for Tumor Relapse [Doi: 10.4143/crt.2018.214] | |
| EMBO?Molecular Medicine | Rescuing ocular development in an anophthalmic pig by blastocyst complementation [Pubmed: 30446498] |
| Biological & Pharmaceutical Bulletin | Zhongfenggao protects brain microvascular endothelial cells from oxygen-glucose deprivation/reoxygenation-induced injury by angiogenesis [Pubmed: 30518742] |
| Journal of Biological Sciences | Maged Mohamed Abd-Elhakim Barakat, Noha Ahmed El-Boghdady, Ebtehal Kamal Eldin Farrag, Ataa Abdelhalim Said and Sylvia Edward Shaker [] |
| International Journal of Immunopathology and Pharmacology | Effect of voluntary running on expression of myokines in brains of rats with depression [Pubmed: 30834799] |
| Journal of Biological Sciences | Protective and Curative Effects of Bombax ceiba Flower and Ziziphus spina christi Fruit Extracts on Gastric Ulcer [] |
| Journal of Geriatric?Oncology | Serum biomarkers for predicting overall survival and early mortality in older patients with metastatic solid tumors [Pubmed: 30952517] |
| International Journal of Oncology | Evaluation of pro?and anti?tumor effects induced by three colony?stimulating factors, G?CSF, GM?CSF and M?CSF, in bladder cancer cells: Is G?CSF a friend of bladder?… [] |
| Journal of Cosmetic Dermatology | Whitening effects of cosmetic formulation in the vascular component of skin pigmentation [Pubmed: 31074159] |
| International Journal of Ophthalmology | A novel xeno-free culture system for human retinal pigment epithelium cells [Pubmed: 31024807] |
| Journal of Experimental & Clinical Cancer Research | Mammalian Eps15 homology domain 1 potentiates angiogenesis of non-small cell lung cancer by regulating β2AR signaling [Pubmed: 31023336] |
| Neuroendocrinology | Strong antitumor activity of bevacizumab and aflibercept in Neuroendocrine Carcinomas: In-depth preclinical study [Pubmed: 31030198] |
| JOURNAL OF PERIODONTOLOGY | A disintegrin‐like and metalloproteinase with thrombospondin‐1 (ADAMTS‐1) levels in gingival crevicular fluid correlate with vascular endothelial growth factor‐A?… [Pubmed: 31020669] |
| Neurochemical research | Expression of Vascular Endothelial Growth Factor in the Rat Brain after Perinatal Hypoxia and Pharmacological Correction [] |
| Molecular Medicine Reports | IL?17A promotes CXCR2?dependent angiogenesis in a mouse model of liver cancer [Pubmed: 31173199] |
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| BioMed Research International | Technical Verification and Assessment of Independent Validation of Biomarker Models for Endometriosis [Pubmed: 31428634] |
| Nutrients | Cardioprotective Effect of a Virgin Olive Oil Enriched with Bioactive Compounds in Spontaneously Hypertensive Rats [Pubmed: 31357464] |
| Genet Test Mol Biomarkers | Associations Between Genetic Polymorphisms in the VEGFA, ACE, and SOD2 Genes and Susceptibility to Diabetic Nephropathy in the Han Chinese [Pubmed: 31524543] |
| ACS Applied Materials & Interfaces | Tazarotene Released from Aligned Electrospun Membrane Facilitates Cutaneous Wound Healing by Promoting Angiogenesis [Pubmed: 31503444] |
| Journal of Ethnopharmacology | BuZangTongLuo decoction improved hindlimb ischemia by activating angiogenesis and regulating gut microbiota in diabetic mice [Pubmed: 31654796] |
| BIOFACTORS | Ginkgolide B and bilobalide promote the growth and increase β‐catenin expression in hair follicle dermal papilla cells of American minks [Pubmed: 31520488] |
| Acta Biomaterialia | Silicon substituted hydroxyapatite/VEGF scaffolds stimulate bone regeneration in osteoporotic sheep [Pubmed: 31678741] |
| Folia Morphologica | Beneficial effects of voluntary over forced exercise on skeletal muscle structure and myokines expression [Pubmed: 31802473] |
| Scientific Reports | Association between Upper-airway Surgery and Ameliorative Risk Markers of endothelial function in obstructive Sleep Apnea [Pubmed: 31882827] |
| ARCHIVES OF GYNECOLOGY AND OBSTETRICS | H19 regulates angiogenic capacity of extravillous trophoblasts by H19/miR-106a-5p/VEGFA axis [Pubmed: 32107606] |
| BMC Cancer | Syntenin overexpression in human lung cancer tissue and serum is associated with poor prognosis [Pubmed: 32106836] |
| Biomed Pharmacother | Soufeng Yuchuan decoction mitigates the ovalbumin-induced lung damage in a rat model of asthma [Pubmed: 32036215] |
| EBioMedicine | Canagliflozin impairs blood reperfusion of ischaemic lower limb partially by inhibiting the retention and paracrine function of bone marrow derived … [Pubmed: 31981975] |
| Clinical Hemorheology and Microcirculation | Nonselective alpha-/beta-AR antagonists can inhibit pericyte proliferation, migration, and secretion in vitro [Pubmed: 32224529] |
| Molecular Medicine Reports | Long non?coding RNA NORAD regulates angiogenesis of human umbilical vein endothelial cells via miR?590?3p under hypoxic conditions [Pubmed: 32323787] |
| Chinese medicine | The curative effects of the traditional Chinese herbal medicine “Jinchuang ointment” on excisional wounds [Pubmed: 32377230] |
| FASEB JOURNAL | Cyclin G2 upregulation impairs migration, invasion, and network formation through RNF123/Dvl2/JNK signaling in the trophoblast cell line HTR8/SVneo, a possible?… [Pubmed: 33205477] |
| Acta Histochem | Paeoniflorin accelerates foot wound healing in diabetic rats though activating the Nrf2 pathway [Pubmed: 33166863] |
| Reproductive Sciences | Maternal Serum VEGF Predicts Abnormally Invasive Placenta Better than NT-proBNP: a Multicenter Case-Control Study [Pubmed: 33025531] |
| Life Sci | Circular RNA COL1A2 promotes angiogenesis via regulating miR-29b/VEGF axis in diabetic retinopathy [Pubmed: 32497630] |
| ACS NANO | Gold Nanoparticles Induce Tumor Vessel Normalization and Impair Metastasis by Inhibiting Endothelial Smad2/3 Signaling [Pubmed: 32413258] |
| Neuropsychiatric Disease and Treatment | Characterization of Endothelial Cells Associated with Cerebral Arteriovenous Malformation [Pubmed: 32368063] |
| Scientific Reports | Molecular mechanisms of synergistic action of Ramucirumab and Paclitaxel in Gastric Cancers cell lines [Pubmed: 32346056] |
| carbohydrate polymers | Effect of Chitosan oligosaccharides on ischemic symptom and gut microbiota disbalance in mice with hindlimb ischemia [Pubmed: 32475560] |
| Cutaneous and Ocular Toxicology | Isotretinoin does not alter VEGF-A and VEGF-C levels: Do retinoids behave differently in dose-dependent and/or in vivo/in vitro conditions? [Pubmed: 32722957] |
| Menoufia Medical Journal | Study of serum level of vascular endothelial growth factor in patients with hepatocellular carcinoma [] |
| Acta Scientific Women's Health | Modulatory Effects of Taurine Combined with Letrozole on Ehrlich Ascites Carcinoma in Mice [] |
| Indian Journal of Public Health Research & Development | Enhanced Fibrin-Lysis in Grade-1 Dengue Haemorrhagic Fever [] |
| Materials Science and Engineering: C | Cell-modified bioprinted microspheres for vascular regeneration [] |
| Strawberry (Fragaria x ananassa) leaf extract reduces brain damage in diabetic male rats [] | |
| Stem Cell Reviews and Reports | Prospects on the Potential In Vitro Regenerative Features of Mechanically Treated-Adipose Tissue for Osteoarthritis Care [33469783] |
| Advanced Healthcare Materials | Accelerated Bone Regeneration by MOF Modified Multifunctional Membranes through Enhancement of Osteogenic and Angiogenic Performance [33448103] |
| Aesthet Surg J | Adipose-Derived Stem Cells Improve the Aging Skin of Nude Mice by Promoting Angiogenesis and Reducing Local Tissue Water [33428732] |
| INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | In-vivo evaluation of alginate-pectin hydrogel film loaded with simvastatin for diabetic wound healing in Streptozotocin-induced diabetic rats [33421467] |
| Eur J Pharmacol | Lactucaxanthin protects retinal pigment epithelium from hyperglycemia-regulated hypoxia/ER stress/VEGF pathway mediated angiogenesis in ARPE-19 cell and rat ?- [33705802] |
| Acta Biomater | Highly interconnected inverse opal extracellular matrix scaffolds enhance stem cell therapy in limb ischemia [33878473] |
| Journal of Tissue Engineering | Therapeutic potential of adipose-derived mesenchymal stem cell exosomes in tissue-engineered bladders [33868627] |
| EXPERIMENTAL EYE RESEARCH | Astaxanthin mediated regulation of VEGF through HIF1|á and XBP1 signaling pathway: An insight from ARPE-19 cell and streptozotocin mediated diabetic rat model [33789142] |
| Randomized Controlled Trial | Effect of Freeze-Dried Amnion Graft on Cytokines in Uterine Exudates Following Hysteroscopic Adhesiolysis of Severe Intrauterine Adhesions [28170094] |
| cancer communications | Programmed death ligand?\1 regulates angiogenesis and metastasis by participating in the c?\JUN/VEGFR2 signaling axis in ovarian cancer [33939321] |
| ?D1ú??éú3??§ó???éú3?2??ó?? | VEGFA/VEGFR2 ?úD?êó???à·????òòê×é?ˉ?a1üéú3é?Dμ?±í′??°×÷ó? [] |
| Chinese Journal of Parasitology and parasitic diseases | Expression and angiogenic effect of VEGFA/VEGFR2 in mice hepatic metacestode tissue of Echinococcus multilocularis [] |
| International Journal of Life science and Pharma Research | Artificial Sweeteners Alter Early Vitelline Vessel Development in Chick Embryo.(2021) [] |
| Biomed Mater | Preclinical efficacy study of a porous biopolymeric scaffold based on (gelatin-hyaluronic acid-chondroitin sulfate) in a porcine burn injury model: Role of critical?… [34384056] |
| J Cell Mol Med | Mesenchymal stem cells from different sources show distinct therapeutic effects in hyperoxia‐induced bronchopulmonary dysplasia in rats [34322990] |
| J Biochem Mol Toxicol | Thymoquinone upregulates miR‐125a‐5p, attenuates STAT3 activation, and potentiates doxorubicin antitumor activity in murine solid Ehrlich carcinoma [34605108] |
| Bioengineered | MicroRNA-934 facilitates cell proliferation, migration, invasion and angiogenesis in colorectal cancer by targeting B-cell translocation gene 2: Running title: miR934?… [34699325] |
| ACS Biomater Sci Eng | Polydopamine-Coated Poly(l-lactide) Nanofibers with Controlled Release of VEGF and BMP-2 as a Regenerative Periosteum [34472855] |
| Cells | A-Kinase Anchoring Protein 2 Promotes Protection against Myocardial Infarction [34831084] |
| J Basic Clin Physiol Pharmacol | Anti-atherosclerotic activity of aqueous extract of Ipomoea batatas (L.) leaves in high-fat diet-induced atherosclerosis model rats [Pubmed:34986543] |
| Stem Cell Res Ther | A dual role of HIF1α in regulating osteogenesis–angiogenesis coupling [Pubmed:35123567] |
| American Journal of Translational Research | Curcumin treats endometriosis in mice by the HIF signaling pathway [Pubmed:35559378] |
| Clinical and Experimental Immunology | Clinical significance of differential serum-signatures for early prediction of severe dengue among Eastern Indian patients [Pubmed:35348620] |
| Medicina | Assessment of the RANTES Level Correlation and Selected Inflammatory and Pro-Angiogenic Molecules Evaluation of Their Influence on CRC Clinical Features: A?… [Pubmed:35208526] |
| Molecular Biology Reports | Umbilical cord-derived mesenchymal stem cell conditioned medium reverses neuronal oxidative injury by inhibition of TRPM2 activation and the JNK signaling?… [Pubmed:35585377] |
| Biomaterials Advances | Human adipose-derived stem cell-loaded small intestinal submucosa as a bioactive wound dressing for the treatment of diabetic wounds in rats [] |
| Biointerface Research in Applied Chemistry | Beetroot Improves the Therapeutic Efficacy of Bone Marrow-Derived Mesenchymal Stem Cells in Preventing Cisplatin Induced Nephrotoxicity in Male Rats [] |
| Research Square | DMOG attenuates steroid-associated endothelial progenitor cell impairment and osteonecrosis of the femoral head via regulating HIF-1α signaling pathway in?… [] |
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