補體成分5(C5)單克隆抗體
Monoclonal Antibody to Complement Component 5 (C5)
CPAMD4; C5a anaphylatoxin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4
- 編號UMAB969Hu21
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(克隆號)C5
- Ig亞型 IgG1Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標記物無標記物
- 免疫原 RPB969Hu01-補體成分5(C5)重組蛋白
- 緩沖液成份磷酸鹽緩沖液（pH7.4,含有0.02% NaN3和50%甘油）
- 性狀液體
- 濃度1mg/mL
- 且適物種-
- 應用WB
如果抗體需用于流式細胞術(shù)，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 321 ¥ 750 ¥ 1071 ¥ 2678 ¥ 10710
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Western Blot; Sample: Human Plasma
Primary Ab: 0.2μg/ml Mouse Anti-Human C5 Antibody
Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
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通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
該抗體是針對C5的小鼠單克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別C5。
用法
Western blotting: 0.01-2μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應用(僅供研究使用，不用于臨床診斷！) |
| URPB969Hu01 | 補體成分5(C5)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UAPB969Hu02 | 補體成分5(C5)活性蛋白 | Cell?culture;?Activity?Assays. |
| URPB969Hu02 | 補體成分5(C5)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAB969Hu01 | 補體成分5(C5)多克隆抗體 | WB; IHC |
| UPAB969Hu02 | 補體成分5(C5)多克隆抗體 | WB; IHC; ICC; IP. |
| ULAB969Hu71 | 補體成分5(C5)多克隆抗體(生物素標記) | WB; IHC; ICC. |
| UMAB969Hu22 | 補體成分5(C5)單克隆抗體 | WB |
| UMAB969Hu21 | 補體成分5(C5)單克隆抗體 | WB |
| USEB969Hu | 補體成分5(C5)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMB969Hu | 補體成分5(C5)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Journal of Clinical Immunology | Complement activation contributes to the injury and outcome of kidney in human anti-glomerular basement membrane disease. [PubMed: 22941511] |
| Journal of Neuroimmunology | Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitis [Pubmed:27235358] |
| Cancer Letters | Complement C5a/C5aR pathway potentiates the pathogenesis Q5 of gastric cancer by down-regulating p21 expression [pubmed:29031586] |
| Proteomics?Clinical?Applications | iTRAQ‐Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism [Pubmed:29274201] |
| American journal of physiology. Endocrinology and metabolism | Impaired insulin signaling in the B10.D2-Hc H2 H2-T18/oSnJ mouse model of complement factor 5 (C5) deficiency [Pubmed: 31084499] |
| Proteomics Clinical Applications | Comparative proteomics analysis of serum proteins in gestational diabetes during early and middle stages of pregnancy [Pubmed: 31162828] |
| Aging | C5aR deficiency attenuates the breast cancer development via the p38/p21 axis [Pubmed: 32669478] |
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